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I discovered Oak Leaf Blister today on a client's Live Oak. This hasn't been a bad year for the disease. This disease is favored by cool, moist conditions when the leaves are coming out. The "blisters" will turn brown as the season progresses. Severe infections may cause the leaves to fall. The disease rarely warrants control. Once symptoms develop, fungicides are ineffective for the current season. They can be apply as a preventative the following year to lessen the severity.